Before you choose the VTT that is best for you, it might make sense to look over this short summary chart that compares the primary named features. I know it can be expanded out further since sometimes a single line item on a chart doesn't adequately describe or convey the importance of the item at work. In order to fully compare the two, it might be worth checking out the Fantasy Grounds and relying upon the 30-day money back guarantee if you are unsatisfied for any reason. You can also try the free version of Roll20. At the end of the day, there is a limited free version and a monthly subscription version of each. With FG, you can buy a 1-time license if you don't want to pay any ongoing subscriptions.
This chart focuses primarily on D&D fifth edition, but each system is capable of running nearly any game system you want to run. Fantasy Grounds has secured the most official licenses of any other system, so that will probably weigh on your decision as well if you plan to run Call of Cthulhu, Savage Worlds or one of the many other systems we officially support. If you intend to build everything on your own, then your focus will likely fall on which VTT gives you the best options to build from or the one with the best community mods available for you to use.
Without further ado, here is the Roll20 vs Fantasy Grounds comparison chart.
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